Plain-English peptide research. Affiliate links are disclosed.

Compound Profiles

Clear guides to individual compounds

Each profile explains what a compound is, how researchers think it works, what studies found, and what remains unknown. It also gives its current UK legal status.

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BPC-157

Also cited as Body protection compound 157

Synthetic pentadecapeptide

A laboratory-made peptide made of 15 amino acids. Almost all published research involved cells or rodents rather than people.

Research stage: Early research in cells and animals

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CJC-1295

Also cited as CJC-1295 with DAC / modified GRF

Long-acting growth-hormone-releasing hormone analogue

A modified growth-hormone-releasing peptide designed to last longer in the blood. Only early-phase human data was published before development stopped.

Research stage: Phase 1 results published; development discontinued

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DSIP

Also cited as Delta sleep-inducing peptide

Nine-amino-acid neuropeptide

A peptide isolated from rabbit brain in the 1970s. Early sleep findings were never reliably reproduced.

Research stage: Small historic human studies; not reproduced

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GHK-Cu

Also cited as Copper tripeptide-1

Copper-binding tripeptide

A small, naturally occurring peptide that binds copper. Researchers mainly studied it in skin cells and gene activity experiments.

Research stage: Mostly cell research, with a few small human skin studies

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GHRP-2

Also cited as Pralmorelin

Growth hormone secretagogue

A small peptide that triggers growth hormone release. In Japan it was approved as a diagnostic test rather than a treatment.

Research stage: Approved as a diagnostic agent in Japan; no treatment authorisation

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GHRP-6

Growth hormone secretagogue

One of the earliest growth-hormone-releasing peptides studied. Human work stayed at the level of short hormone-response experiments.

Research stage: Early human physiology studies only

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HGH

Also cited as Human growth hormone / somatropin

Recombinant protein hormone

A hormone the pituitary gland makes. A licensed prescription version treats defined deficiency conditions; anti-ageing claims are not supported by trials.

Research stage: Licensed medicine for defined deficiency conditions

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IGF-1 LR3

Also cited as Long R3 IGF-1

Modified insulin-like growth factor analogue

A laboratory reagent version of IGF-1, altered to last longer in cell culture. It has never been studied in human trials.

Research stage: Laboratory reagent; no human trials published

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Ipamorelin

Growth hormone secretagogue (ghrelin receptor agonist)

A laboratory-made peptide that acts on the ghrelin receptor. Early human research ended without the compound becoming an authorised medicine.

Research stage: Early human research; development stopped

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Kisspeptin

Also cited as Metastin / kisspeptin-54

Hypothalamic reproductive hormone

A natural brain hormone that sits at the top of the reproductive hormone chain. University research groups have studied it in people.

Research stage: Early-phase academic human studies published

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KPV

Also cited as Lys-Pro-Val

Alpha-MSH fragment tripeptide

A three-amino-acid fragment of a natural hormone. Published research on inflammation is in cells and rodents only.

Research stage: Pre-clinical only

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Mazdutide

Also cited as IBI362 / LY3305677

Dual GLP-1 / glucagon receptor agonist

An experimental peptide based on a natural gut hormone. Researchers studied it mainly in phase 2 and phase 3 trials in China.

Research stage: Phase 3 results reported in Chinese study groups

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Melanotan 1

Also cited as Afamelanotide

Selective MC1 receptor agonist

The peptide behind a licensed medicine for a rare light-sensitivity disorder. Research-grade material is not that medicine.

Research stage: Phase 3 results published; licensed for one rare condition

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Melanotan 2

Also cited as MT-2

Non-selective melanocortin receptor agonist

A peptide that stimulates pigment cells. It was never approved anywhere, and UK health bodies have issued warnings about it.

Research stage: No completed controlled trials; safety concerns documented in case reports

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MOTS-c

Mitochondrial-derived peptide

A peptide made of 16 amino acids and encoded by mitochondrial DNA. Researchers studied it mainly in metabolism and exercise models.

Research stage: Early cell and animal research, plus observational human studies

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NAD+

Also cited as Nicotinamide adenine dinucleotide

Coenzyme (not a peptide)

A coenzyme every cell uses to move energy around. Most published human work studied precursor molecules rather than NAD+ itself.

Research stage: Multiple small human trials of precursors published

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Oxytocin

Natural nine-amino-acid hormone

A hormone the body makes for childbirth and milk release. A prescription medicine version exists; research-grade material is not that medicine.

Research stage: Licensed medicine for obstetric use; behavioural trials inconclusive

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Pal-GHK

Also cited as Palmitoyl tripeptide-1

Cosmetic peptide

A fat-modified version of the GHK tripeptide used in skincare. Human data comes mainly from tests of complete formulations.

Research stage: Cosmetic formulation studies only

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PT-141

Also cited as Bremelanotide

Melanocortin receptor agonist

A peptide that activates melanocortin receptors. Phase 3 trial results were published, and it was authorised for one use in the United States.

Research stage: Phase 3 results published; licensed for one condition in the United States

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Retatrutide

Also cited as LY3437943

Triple incretin receptor agonist

An experimental peptide that acts on three hormone receptors. Researchers studied it in phase 2 trials involving weight and blood sugar.

Research stage: Phase 2 results published; phase 3 trials under way

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Selank

Tuftsin-derived neuropeptide

A peptide developed in Russia and studied there for anxiety. Very little of that research appeared in international peer-reviewed journals.

Research stage: Regional clinical reports only

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Sermorelin

Also cited as GRF (1-29)

Growth-hormone-releasing hormone analogue

A short copy of the body's own growth-hormone-releasing hormone. It was once sold as a medicine for testing growth hormone in children.

Research stage: Historic licensed diagnostic use overseas; no current authorisation

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SNAP-8

Also cited as Acetyl octapeptide-3

Cosmetic peptide

An eight-amino-acid peptide used in cosmetic formulations. Published evidence is mostly laboratory work and manufacturer testing.

Research stage: Cosmetic ingredient testing; little independent research

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SS-31

Also cited as Elamipretide

Mitochondria-targeted tetrapeptide

A four-amino-acid peptide aimed at the energy-producing parts of cells. It reached late-stage trials in rare mitochondrial diseases with mixed results.

Research stage: Phase 3 results published in rare disease groups

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TB-500

Also cited as Thymosin beta-4 fragment

Peptide fragment of thymosin beta-4

A laboratory-made piece of thymosin beta-4, a natural protein. Researchers mainly examined it in early cell and animal studies.

Research stage: Early cell and animal research on TB-500; early human research on the full protein

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Tesamorelin

Growth hormone-releasing hormone analogue

A laboratory-made version of a natural hormone. Human trials were published, but it is not licensed as a medicine in the UK.

Research stage: Phase 3 results published; licensed for one condition in the United States

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None of the compounds described here is licensed as a medicine in the United Kingdom, and none is approved for human or animal use. These pages are educational reference only and are not medical advice.