Sermorelin

What it is

Sermorelin is a laboratory-made copy of the first 29 amino acids of growth-hormone-releasing hormone, the signal the brain uses to tell the pituitary gland to release growth hormone.

How researchers think it works

Studies found that sermorelin acted on the same receptor as the natural hormone, prompting the pituitary gland to release stored growth hormone rather than adding hormone from outside.

What has research seen in people?

Human studies used it mainly as a test of whether the pituitary gland could release growth hormone, and it was once sold for exactly that purpose.

Small studies in older adults reported short-term rises in growth hormone and IGF-1 readings, but not improvements in health, strength or body composition.

The record is small and dated, and no current UK licence exists.

Where this material is listed

For laboratory research use only. Not a medicine and not for human or animal use.

Research materialSermorelin£49.99View listing ›

Veritide does not sell or supply anything. This links to a third-party UK laboratory supplier; we may earn a commission if you buy through it, at no extra cost to you. Materials are sold for laboratory research use only and are not licensed medicines.

What studies have found

• Published clinical work from the 1990s used it as a test of whether the pituitary gland could release growth hormone, and it was marketed for that purpose in the United States before being discontinued.
• Small studies in older adults reported short-term rises in growth hormone and IGF-1 markers. Researchers did not report long-term health outcomes.

What we still do not know

• The human record is small, mostly decades old, and focused on short-term hormone measurements rather than whether people were healthier.
• The product that once held a licence was withdrawn from the market for commercial reasons, and no current licence exists in the UK.

Sources

• PubMed — sermorelin literature index ›